For your safety, use the official rental car agencies offered by the Santiago airport:
Alamo
Counters are located on the first level, Central International Hall; and at Domestic & International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1370, or (56 2) 690 1383, or (56 2) 690 1513.
Avis
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1382, or (56 2) 690 1318.
Budget
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1233, or (562) 690 1489, or (562) 690 1386.
Econorent
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1287, or (56 2) 690 1212.
Hertz
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 601 0477, or (56 2) 690 1384, or (56 2) 690 1029.
Rosselot
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1374.
Alamo
Counters are located on the first level, Central International Hall; and at Domestic & International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1370, or (56 2) 690 1383, or (56 2) 690 1513.
Avis
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1382, or (56 2) 690 1318.
Budget
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1233, or (562) 690 1489, or (562) 690 1386.
Econorent
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1287, or (56 2) 690 1212.
Hertz
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 601 0477, or (56 2) 690 1384, or (56 2) 690 1029.
Rosselot
Counters are located on the first level, Central International Hall; and at Domestic and International Arrivals. Open daily 6:30am-10:30pm. Tel: (56 2) 690 1374.