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can anyone recommend the best way to travel from the airport to Greenville please?
It's over a 4 hour drive. The best way is to fly American Airlines nonstop. There is no reasonable other public transit route. So your only options are flying and driving. Taking the Greyhound bus takes 14 hours as you have to make a nearly 6 hour stop in Rocky Mount.
Sorry, that answer was for getting form Charlotte to Greenville. You should still probably drive.
Thanks for clarifying ZAP. I travelled by Greyhound bus service. Made it in one piece - just!