To get from Tambo Airport to your destination you can rent a car (rental cars desks are located in Parkade 2), or take a taxi, a bus or a train:  A public Transport Information desk is located at Domestic Arrivals (at public concourse). 
By Train:
The Central Terminal building (a level below Departures) houses the The Gautrain station, where you can take the train to Sandton &transfer there to a train into Johannesburg - a total trip of 25 mins. For more information open:  gautrain.co.za
By Bus:
Five bus lines by Metrobus & Putco stop at the Airport twice a day, in the morning and evening. 

Google Plus One